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PERQUE Endura/PAK Guard

L-Glutamine with PAK, uinque, patented formula, that does NOT build up to glutamate which supports digestive health, stamina, and mental clarity

Benefits from two decades of this unique, patented formula, PERQUE Endura/PAK Guard if you:
  1. Need more endurance
  2. Are constantly fatigued
  3. Feel mentally sluggish
  4. Want a faster recovery after exercise.*

Unique with patent number: 6,545,044 B2 date of Patent April 8, 2003

L-GLUTAMINE+PAK without glutamate build-up

Glutamine is a primary fuel for the intestines, muscles, brain, and liver. PAK naturally recycles L-glutamine, so the body can use it over and over again. Because of this combination, one gram of the L-glutamine + PAK in Endura/PAK Guard is worth five to 10 grams of any other glutamine. By recycling L-glutamine + PAK, Endura/PAK Guard protects against glutamate build-up.*

This supplement is an exceptional option for those with intestinal irritations.* Its ingredients assist in the regeneration of the intestines surface cells; this is particularly important due to the fact that intestinal surfaces are quite vulnerable to abrasion and erosion caused by mechanical action, toxins, or atypical bacteria, and symptoms such as diarrhea or chronic constipation may result.*

Diagnosing Chronic Fatigue Syndrome (CFS)

When is it "garden-variety" tiredness, and when is it chronic fatigue syndrome (CFS)? CFS is characterized, according to the U.S. Centers for Disease Control (CDC), by the following symptoms:

  • Persistent fatigue for over six months
  • Sore throat
  • Tender lymph nodes
  • Muscle pain
  • Impaired memory and ability to concentrate
  • Pain in many joints without swelling or redness
  • Headaches, or
  • Severe malaise lasting over 24 hours after exercise or exertion

Even after years of research, the actual cause of CFS is still not known.* Before developing a treatment program, physicians are advised to examine the CFS patient to identify possible causes. Often, food allergies, or dysfunction of the thyroid, pituitary, or adrenal glands are implicated in fatigue.* One study of CFS patients noted that their adrenal glands had shrunk by 50%, indicating significant atrophy.* PERQUE Adreno Distress Guard may benefit persons with adrenal gland support.* Reduced oxygen delivery to the muscles and vitamin B deficiencies have also been observed in CFS.* PERQUE Life Guard is best for safer B Vitamin deficiencies.* Waking up digestion is also considered with PERQUE DigestivAide and PERQUE Digesta Guard Forte. PERQUE Endura/PAK Guard is observed clinically to benefit some people with CFS.*

  1. Heap LC, Peters TJ, Wessely S: Vitamin B status in patients with chronic fatigue syndrome. J R Soc Med 1999; 92(4): 183- 185.
  2. McCully KK, Natelson BH: Impaired oxygen delivery to muscle in chronic fatigue syndrome. Clin Sci (Colch) 1999; 95(5): 603-608.
  3. Scott LV, Teh J, Reznek R, Martin A, Sohaib A, Dinan TG: Small adrenal glands in chronic fatigue syndrome: a preliminary computer topography study. Psychoneuroendocrinology 1999; 24(7): 759-768.
  4. Albrecht J, Norenberg MD Glutamine: a Trojan horse in ammonia neurotoxicity. Hepatology 2006 Oct;44(4):788-94.
  5. Soondrum K, Hinds R. Management of intestinal failure. Indian J Pediatr 2006 Oct;73(10):913-8. 6. Wu XQ, Shu LH, Sun M,Wang H, Gao H. [Effect of glutamine on apoptosis of the small intestine in young rats with endotoxemia and its mechanism.]
Supplement Facts: (no hidden or inactive ingredients)

Supplement Facts (no hidden or inactive ingredients):
3 capsules contain:
L-glutamine (free form) 1,500mg
PAK (pyridoxal alpha-ketoglutarate) 500mg
Rice flour (organic) 90mg
Magnesium 13mg
—(as C16 and C18 alkyls from whole, untreated palm fruit and leaf)
Vegetable capsules 291mg
Contains NO: citrus, MSG, wheat, gluten, corn, starch, sugar, wax, soy, yeast, zein, sulfate, phosphates (other than coenzymes), preservatives, casein or other milk derivatives. NO GMOs.

Recommended Use:
Adults: As a dietary supplement, take three (3) capsules on an empty stomach upon rising and three (3) capsules before bed or as directed by your health professional. Plus, take three (3) additional capsules prior to exercise.

If you are pregnant or nursing, please consult your healthcare professional before using this product. Keep out of the reach of children.

click here for PDF:  PERQUE EnduraPAK Guard

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Videos from Dr Russell Jaffe, PERQUE Scientist & Founder

The PERQUE Guarantee

PERQUE has been specifically formulated based on higher standards of quality listed below. When comparing:

  • All PERQUE products come with a 100% unconditional money-back guarantee — the strongest guarantee in the natural health industry.
  • Every PERQUE product provides 100% potency and activity for its entire shelf life. PERQUE formulas are designed for exceptional delivery and stability.
  • Only the exact delivery forms of nutrients shown in clinical studies to be effective are used in PERQUE formulas with NO substitutions.
  • By using high precision control of temperature and pressure in the manufacturing process, all PERQUE products, including tabsules, dissolve rapidly (15-20 minutes in the stomach), allowing superior uptake and rapid results as well as eliminating digestive irritation found with other brands.
  • Full label disclosure is provided for all PERQUE products — no hidden or inactive ingredients.
  • In order for a nutrient to be brought into your body, it must be transported. Every PERQUE product is activated with the same potent transporters that are used by nature and in food to ensure full bioavailability or 100% uptake.
  • The biologically preferred form of an ingredient is always used to enhance activity, produce energy, and deliver direct results
  • All PERQUE products are allergen-free and contaminant-free, and do not contain citrus, MSG, wheat/gluten, corn/zein/starch, dairy/casein/milk derivatives (except meal powders), yeast, soy, sulfate, phosphates (other than coenzymes) or preservatives.
  • PERQUE products do not contain genetically modified organisms (GMOs)
  • All PERQUE ingredients are plant-based except the human probiotic strains, distilled lipids, and PERQUE Joint Guard extracts.
  • Every PERQUE product is produced following or exceeding the FDA’s pharmaceutical GMP (Good Manufacturing Practices) regulations.


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* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.