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PERQUE Vessel Health Guard

Protects arteries and veins with vitamins B12 as hydroxocobalamin, B6 and Folate which promotes healthier homocysteine, a marker for stroke*

PERQUE Vessel Health Guard
  • Formulated as a lozenge for rapid uptake and quicker results.*
  • May support healthier homocysteine level, which is a marker for stroke.*
Healthy, flexible blood vessels and blood flow is essential to:
  1. Bring fuel and remove toxic waste from vital organs like your heart, brain, intestines, muscles, kidneys, and liver.*
  2. Keep blood vessels elastic and flexible for your full lifespan.*
  3. Keep brain function clear and well-connected.*
  4. Promote blood vessel health to avoid heart and blood vessel hardening, Alzheimer’s senility, and thrombosis (platelet clumps and clots that block blood flow) linked to stroke and heart attacks.*

Homocysteine levels tell if you have enough of certain nutrients that activate body catalysts (enzymes) essential for repairing blood vessels. With homocysteine lower than 6

  • Your blood vessels are healthier.
  • Your risk of excessive blood clotting (thrombosis) in the brain (stroke) or heart (coronary occlusion, blocked heart artery) or major blood vessel (arteriosclerosis or atherosclerosis) is lower
  • Reduction or elimination of homocystinuria (loss of sulfur compounds in the urine).
  • Reduction or elimination of excess methylmalonic acid (a marker of inefficient metabolism).
  • Overall improvement in nutrient uptake by activating enzyme catalysts needed for nutrient assimilation and action.
  • Correction of dietary nutrient deficits.*
What about measuring B-12 levels?

The standard (Schilling) B-12 test measures the amount of B-12 in the serum. This does not correlate well with the functional amount in your cells, which is why homocysteine levels are functionally predictive of B-12 need. For example, all people on “hypoglycemic” medications show a decrease in cellular B-12 and an increase in homocysteine levels even though their standard B-12 tests remain unchanged.*


  1. Tawakol A, Migrino RQ, Aziz KS, Waitkowska J, Holmvang G, Alpert NM, Muller JE, Fischman AJ, Gewirtz H. High-dose folic acid acutely improves coronary vasodilator function in patients with coronary artery disease. J Am Coll Cardiol 2005 May 17; 45(10):1580-4.
  2. Vermeulen EG, Stehouwer CD, Twisk JW, van den Berg M, de Jong SC, Mackaay AJ, van Campen CM, Visser FC, Jakobs CA, Bulterjis EJ, Rauwerda JA. Effect of homocysteine-lowering treatment with folic acid plus vitamin B6 on progression of subclinical atherosclerosis: a randomised, placebo-controlled trial. Lancet 2000 Feb 12; 355(9203):517-22.
  3. Refsum H, et. al. Facts and recommendations about total homocysteine determinations: an expert opinion. Clin Chem 2004 Jan;50(1):3-32.
  4. Doshi S, et. al. Folate improves endothelial function in patients with coronary heart disease. Clin Chem Lab Med 2003; 41(11):1505-1512.
  5. Weiss N, et. al. Influence of hyperhomocysteinemia on the cellular redox state--impact on homocysteine-induced endothelial dysfunction. Clin Chem Lab Med 2003; 41(11):1455-1461.
  6. Schroecksnadel K, et. al. Hyperhomocysteinemia and immune activation. Clin Chem Lab Med 2003; 41(11):1438-1443.
  7. Ueland PM, Monsen AL. Hyperhomocysteinemia and B-vitamin deficiencies in infants and children. Clin Chem Lab Med 2003; 41(11):1418-1426.
  8. Balk EM, et. al. Effects of statins on nonlipid serum markers associated with cardiovascular disease: a systematic review. Ann Intern Med 2003; 139(8):670-682.
  9. Gilligan MA. Metformin and vitamin B-12 deficiency. Arch Intern Med. 2002;162:484-485
Supplement Facts: (no hidden or inactive ingredients)

1 lozenge contains the following Energized Nutrients:
Vitamin B-12 (hydroxocobalamin) 2 mg
Folate (as calcium folinate)  4250 mcg DFE
Magnesium ascorbate 30 mg
Vitamin B-6 (pyridoxine) 10 mg
Mannitol 181 mg
Raspberry Flavor 7 mg
100% Whole cherry fruit extract 6 mg
Organic, whole cane juice
Xylitol 20 mg
Magnesium (as C16 and C18 alkyls) 3 mg from whole, untreated palm fruit and leaf
Croscarmellose 19.5 mg

Contains NO: citrus, MSG, wheat, gluten, corn, starch, sugar, soy, yeast, zein, sulfate, phosphates (other than coenzymes), preservatives, casein or other milk derivatives. NO GMOs.

Recommended Use:
Adults: As a dietary supplement, take one (1) to six (6) lozenges daily or as directed by your health professional.

If you are pregnant or nursing, please consult your healthcare professional before using this product. Keep out of the reach of children.

PERQUE Vessel Health Guard

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Videos from Dr Russell Jaffe, PERQUE Scientist & Founder

The PERQUE Guarantee

PERQUE has been specifically formulated based on higher standards of quality listed below. When comparing:

  • All PERQUE products come with a 100% unconditional money-back guarantee — the strongest guarantee in the natural health industry.
  • Every PERQUE product provides 100% potency and activity for its entire shelf life. PERQUE formulas are designed for exceptional delivery and stability.
  • Only the exact delivery forms of nutrients shown in clinical studies to be effective are used in PERQUE formulas with NO substitutions.
  • By using high precision control of temperature and pressure in the manufacturing process, all PERQUE products, including tabsules, dissolve rapidly (15-20 minutes in the stomach), allowing superior uptake and rapid results as well as eliminating digestive irritation found with other brands.
  • Full label disclosure is provided for all PERQUE products — no hidden or inactive ingredients.
  • In order for a nutrient to be brought into your body, it must be transported. Every PERQUE product is activated with the same potent transporters that are used by nature and in food to ensure full bioavailability or 100% uptake.
  • The biologically preferred form of an ingredient is always used to enhance activity, produce energy, and deliver direct results
  • All PERQUE products are allergen-free and contaminant-free, and do not contain citrus, MSG, wheat/gluten, corn/zein/starch, dairy/casein/milk derivatives (except meal powders), yeast, soy, sulfate, phosphates (other than coenzymes) or preservatives.
  • PERQUE products do not contain genetically modified organisms (GMOs)
  • All PERQUE ingredients are plant-based except the human probiotic strains, distilled lipids, and PERQUE Joint Guard extracts.
  • Every PERQUE product is produced following or exceeding the FDA’s pharmaceutical GMP (Good Manufacturing Practices) regulations.


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* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.